Online education has become increasingly popular within higher education. Moving away from the traditional in-class setting, online education provides some benefits including convenience of location, timing of classes, and class size. However, drawbacks of online education include less engagement of students and decreased ability to actively participate within the classroom setting, such as receiving immediate feedback to questions regarding the material presented. Current research validates both traditional and blended learning techniques as effective modes of information acquisition and retention. As the number of online college course offerings increases, the extent to which the online learning environment should be assessed to determine its effect on acquisition and retention.This poster presents the results of a literature review to determine if there is a significant difference between online versus in-class learning based on student acquisition and retention of learned material.