Low power laser is a treatment modality that uses monochromatic, collimated, and coherent light to intervene in a variety of musculoskeletal disorders. Low power laser is commonly used to facilitate tissue healing. The process by which low power laser facilitates tissue healing varies from modulating biological responses of cells to stimulating or inhibiting cellular functions. This project is a review of the literature with respect to the efficacy of low power laser in intervening with the healing of different types of tissues. If efficacy is found, then appropriate parameters relative to the application of low power laser will be discussed.